The advancement of informatics in health has allowed a convergence of digital technologies with health and healthcare, with the goal of improving the efficiency and effectiveness of health services as well as making medicines more personalized and precise. These technologies include solutions for both healthcare providers and patients, ranging from Electronic Health Records, Telemedicine, Mobile Health, Wearable Devices, as well as many emerging Internet-of-Things devices and sensors. Interventions through digital health require a multi-disciplinary domain team involving both informatics and social sciences. This course will provide students with opportunities to explore, analyze, and discuss key issues, principles (both from technical and social science perspectives), approaches, and policies surrounding digital health. The final assignment of this course will task student to work with key health service stakeholders (who would actually share their knowledge throughout the course as well) to investigate and propose a practical digital health solution to tackle a specific health issue.